(19)
(11) EP 4 301 400 A1

(12)

(43) Date of publication:
10.01.2024 Bulletin 2024/02

(21) Application number: 22763997.8

(22) Date of filing: 02.03.2022
(51) International Patent Classification (IPC): 
A61K 38/39(2006.01)
A61K 48/00(2006.01)
 A61P 17/02(2006.01)
A61P 35/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 17/02; A61P 35/00; C12N 2740/16043; C12N 15/113; C12N 2310/14; C12N 2310/531; A61K 38/45; C12Y 207/07049; A61K 38/1709; A61K 31/675; A61K 31/713; A61K 31/502; A61K 31/7068; A61K 31/495; C07K 14/78; C12N 9/1276
 
C-Sets:
  1. A61K 38/45, A61K 2300/00;
  2. A61K 38/1709, A61K 2300/00;
(86) International application number:
PCT/US2022/018563
(87) International publication number:
WO 2022/187391 (09.09.2022 Gazette 2022/36)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 02.03.2021 US 202163155628 P
02.11.2021 US 202163274734 P

(71) Applicant: Reverse Bioengineering, Inc.
Alameda, CA 94501 (US)

(72) Inventor:
  • WEST, Michael, D.
    Mill Valley, CA 94941 (US)

(74) Representative: Bassil, Nicholas Charles et al
Kilburn & Strode LLP Lacon London 84 Theobalds Road
London WC1X 8NL
London WC1X 8NL (GB)

   


(54) METHODS AND COMPOSITIONS USED TO MODIFY CHROMATIN ARCHITECTURE TO REGULATE PHENOTYPE IN AGING AND CANCER