(19)

(11)

EP 4 302 079 A1

(12)

(43) Date of publication: 10.01.2024 Bulletin 2024/02 (21) Application number: 22709771.4 (22) Date of filing: 01.03.2022

(51) International Patent Classification (IPC):  G01N 21/77(2006.01) G01N 21/81(2006.01) G01N 21/78(2006.01) G01N 21/64(2006.01) (52) Cooperative Patent Classification (CPC): G01N 2021/7786; G01N 2021/7779; G01N 21/7746; G01N 2021/772; G01N 21/81; G01N 21/783; G01N 2021/7726; G01N 2021/6434; G01N 2021/6484; G01N 21/7703 (86) International application number: PCT/GB2022/050537 (87) International publication number: WO 2022/185042 (09.09.2022 Gazette 2022/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.03.2021 GB 202102889 (71) Applicant: The University of Nottingham Nottingham, Nottinghamshire NG7 2RD (GB)	(72) Inventors: MORGAN, Stephen Nottingham Nottinghamshire NG7 2RD (GB) LIU, Liangliang Nottingham Nottinghamshire NG7 2RD (GB) KORPOSH, Serhiy Nottingham Nottinghamshire NG7 2RD (GB) CORREIA, Ricardo Nottingham Nottinghamshire NG7 2RD (GB) (74) Representative: Barker Brettell LLP  100 Hagley Road Edgbaston Birmingham, West Midlands B16 8QQ Birmingham, West Midlands B16 8QQ (GB)