(19)
(11) EP 4 308 101 A1

(12)

(43) Date of publication:
24.01.2024 Bulletin 2024/04

(21) Application number: 22723443.2

(22) Date of filing: 20.04.2022
(51) International Patent Classification (IPC): 
A61K 31/198(2006.01)
A61P 29/02(2006.01)
 A61P 25/02(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/198; A61P 25/02; A61P 29/02
(86) International application number:
PCT/EP2022/060375
(87) International publication number:
WO 2022/223590 (27.10.2022 Gazette 2022/43)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 21.04.2021 IT 202100010181

(71) Applicant: Redyneuheart S.r.l.
20123 Milano (IT)

(72) Inventors:
  • FANTUCCI, Piercarlo
    15049 Vignale Monferrato (Alessandria) (IT)
  • GOVONI, Stefano
    27100 Pavia (IT)
  • PASCALE, Alessia Angela
    27100 Pavia (IT)
  • MARCHESI, Nicoletta
    27040 Pinarolo Po (Pavia) (IT)
  • ALLEGRI, Massimo
    24121 Bergamo (IT)
  • VANOLI, Emilio
    22070 Guanzate (Como) (IT)
  • CALVILLO, Laura
    20812 Limbiate (Monza Brianza) (IT)
  • REGGIANI, Paolo
    00197 Roma (IT)
  • PACE, Valentina
    00132 Roma (IT)

(74) Representative: Rapisardi, Mariacristina 
Ufficio Brevetti Rapisardi S.r.l. Via Serbelloni, 12
20122 Milano
20122 Milano (IT)

   


(54) N-ACETYL CYSTEINE FOR NEURAXIAL USE AS A TRKA TYROSINE KINASE RECEPTOR INHIBITOR FOR THE TREATMENT OF ACUTE AND CHRONIC PAIN