(19)
(11) EP 4 308 561 A1

(12)

(43) Date of publication:
24.01.2024 Bulletin 2024/04

(21) Application number: 22807764.0

(22) Date of filing: 10.05.2022
(51) International Patent Classification (IPC): 
C07D 453/02(2006.01)
A61P 3/00(2006.01)
A61P 43/00(2006.01)
A61K 31/439(2006.01)
A61P 25/16(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 43/00; A61P 3/00; C07D 453/02; A61P 25/16
(86) International application number:
PCT/KR2022/006613
(87) International publication number:
WO 2022/240116 (17.11.2022 Gazette 2022/46)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 11.05.2021 KR 20210060942

(71) Applicants:
  • Yuhan Corporation
    Seoul 06927 (KR)
  • Green Cross Corporation
    Yongin-si, Gyeonggi-do 16924 (KR)

(72) Inventors:
  • KIM, Dong-Hoon
    Suwon-si Gyeonggi-do 16684 (KR)
  • JOO, Jae-Eun
    Yongin-si Gyeonggi-do 17097 (KR)
  • SHIN, Seung-Yub
    Seongnam-si Gyeonggi-do 13616 (KR)
  • KWON, Sool-Ki
    Yongin-si Gyeonggi-do 17086 (KR)
  • PARK, Jong-Suk
    Anyang-si Gyeonggi-do 14044 (KR)

(74) Representative: Turner, Craig Robert et al
AA Thornton IP LLP 8th Floor, 125 Old Broad Street
London EC2N 1AR
London EC2N 1AR (GB)

   


(54) NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST GLUCOSYLCERAMIDE SYNTHASE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME