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(11)

EP 4 314 264 A1

(12)

(43) Date of publication: 07.02.2024 Bulletin 2024/06 (21) Application number: 22721526.6 (22) Date of filing: 01.04.2022

(51) International Patent Classification (IPC):  C12N 9/12(2006.01) C12P 19/36(2006.01) C12N 5/10(2006.01) A61P 35/00(2006.01) C12N 15/52(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/1241; A61P 35/00; C12P 19/36; C12N 15/52; C12Y 207/07 (86) International application number: PCT/US2022/023035 (87) International publication number: WO 2022/212832 (06.10.2022 Gazette 2022/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 02.04.2021 US 202163170010 P (71) Applicant: Codexis, Inc. Redwood City, CA 94063 (US)	(72) Inventors: BORRA-GARSKE, Margie, Tabuga Redwood City, California 94063 (US) ALVIZO, Oscar Redwood City, California 94063 (US) MILLER, Lillian, Jasmine Saratoga, California 95070 (US) PETKOVA, Aksiniya, Lyubenova Redwood City, California 94063 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)