(19)
(11) EP 4 323 065 A1

(12)

(43) Date of publication:
21.02.2024 Bulletin 2024/08

(21) Application number: 22789121.5

(22) Date of filing: 13.04.2022
(51) International Patent Classification (IPC): 
A61P 31/14(2006.01)
A61K 39/12(2006.01)
C12N 15/50(2006.01)
 A61K 39/215(2006.01)
C12N 7/04(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 31/14; C12N 2770/20034; A61K 2039/53; A61K 39/12; A61K 2039/575; A61K 2039/572
(86) International application number:
PCT/US2022/071691
(87) International publication number:
WO 2022/221843 (20.10.2022 Gazette 2022/42)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 13.04.2021 US 202163174375 P
25.06.2021 US 202163215172 P
23.09.2021 US 202163247707 P
11.02.2022 US 202263309387 P
25.02.2022 US 202263314074 P

(71) Applicant: Inovio Pharmaceuticals, Inc.
Plymouth Meeting, PA 19462 (US)

(72) Inventors:
  • SMITH, Trevor
    San Diego, California 92103 (US)
  • RAMOS, Stephanie
    Santee, California 92071 (US)
  • MACHADO DE MELLO ANDRADE, Viviane
    San Diego, California 92126 (US)

(74) Representative: Leonard, Thomas Charles 
Kilburn & Strode LLP Lacon London 84 Theobalds Road
London WC1X 8NL
London WC1X 8NL (GB)

   


(54) METHODS OF INDUCING IMMUNE RESPONSE AGAINST SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) VARIANTS OF CONCERN