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EP 4 323 066 A1

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(43) Date of publication: 21.02.2024 Bulletin 2024/08 (21) Application number: 22720905.3 (22) Date of filing: 15.04.2022

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07D 487/04(2006.01) C07D 495/04(2006.01) A61K 31/519(2006.01) C07D 471/04(2006.01) C07D 491/04(2006.01) C07D 513/04(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/04; C07D 487/04; C07D 491/04; C07D 513/04; C07D 495/04; A61P 35/00 (86) International application number: PCT/US2022/071732 (87) International publication number: WO 2022/221866 (20.10.2022 Gazette 2022/42)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 16.04.2021 US 202163175837 P 05.10.2021 US 202163262093 P (71) Applicant: Ikena Oncology, Inc. Boston, Massachusetts 02210 (US)

(72) Inventors: CASTRO, Alfredo C. Boston, Massachusetts 02210 (US) BURKE, Michael J. Boston, Massachusetts 02210 (US) PROUDFOOT, John Newtown, Connecticut 06470 (US) RUPPEL, Sabine K. Boston, Massachusetts 02210 (US) WYNN, Thomas A. Boston, Massachusetts 02210 (US) (74) Representative: Tostmann, Holger Carl  Wallinger Ricker Schlotter Tostmann Patent- und Rechtsanwälte Partnerschaft mbB Zweibrückenstrasse 5-7 80331 München 80331 München (DE)