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EP 4 323 100 A1

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(43) Date of publication: 21.02.2024 Bulletin 2024/08 (21) Application number: 21937166.3 (22) Date of filing: 16.04.2021

(51) International Patent Classification (IPC):  B01J 19/00(2006.01) C12M 3/00(2006.01) C40B 30/04(2006.01) C12M 1/00(2006.01) C40B 30/00(2006.01) (52) Cooperative Patent Classification (CPC): G01N 33/5008; C40B 30/04; G01N 33/54306; C12Q 1/6813 (86) International application number: PCT/US2021/027769 (87) International publication number: WO 2022/220844 (20.10.2022 Gazette 2022/42)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: Plexium, Inc. San Diego, CA 92121 (US)	(72) Inventors: ZHANG, Yi San Diego, CA 92121 (US) LU, Jesse San Diego, CA 92121 (US) PRICE, Alex San Diego, CA 92121 (US) YANG, Pengyu San Diego, CA 92121 (US) VIJAYAN, Kandaswamy San Diego, CA 92121 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)