(19)
(11) EP 4 323 407 A1

(12)

(43) Date of publication:
21.02.2024 Bulletin 2024/08

(21) Application number: 22726324.1

(22) Date of filing: 13.04.2022
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
A61P 25/28(2006.01)
G01N 33/53(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 16/2842; A61K 2039/505; A61P 25/28
(86) International application number:
PCT/US2022/024694
(87) International publication number:
WO 2022/221458 (20.10.2022 Gazette 2022/42)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 13.04.2021 FR 2103793
13.04.2021 US 202163174399 P
16.03.2022 US 202263320655 P
12.04.2022 WO PCT/US2022/024450

(71) Applicant: Biogen MA Inc.
Cambridge, MA 02142 (US)

(72) Inventor:
  • BELACHEW, Shibeshih, Mitiku
    Cambridge, MA 02142 (US)

(74) Representative: Pohlman, Sandra M. 
df-mp Dörries Frank-Molnia & Pohlman Patentanwälte Rechtsanwälte PartG mbB Theatinerstrasse 16
80333 München
80333 München (DE)

   


(54) COMPOSITIONS AND METHODS FOR TREATING CHRONIC ACTIVE WHITE MATTER LESIONS / RADIOLOGICALLY ISOLATED SYNDROME