METHODS OF TREATING OCULAR DISEASES USING AAV2 VARIANTS ENCODING AFLIBERCEPT - Patent 4329721

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(11)

EP 4 329 721 A1

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(43)	Date of publication:
	06.03.2024 Bulletin 2024/10

(21)	Application number: 22729004.6

(22)	Date of filing: 26.04.2022

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International Patent Classification (IPC):

A61K 9/00^(2006.01)
A61K 31/713^(2006.01)
A61K 38/17^(2006.01)
A61P 27/02^(2006.01)
C12N 15/86^(2006.01)

A61K 31/573^(2006.01)
A61K 35/761^(2015.01)
A61K 45/06^(2006.01)
C12N 7/00^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	A61K 9/0048; A61K 31/573; A61K 38/179; A61K 45/06; A61P 27/02; C12N 15/86; C12N 2750/14143; C07K 2319/30; C12N 2830/50; A61K 9/0019; A61K 47/02

	C-Sets:
	A61K 31/573, A61K 2300/00;

(86)	International application number:
	PCT/US2022/071937

(87)	International publication number:
	WO 2022/232790 (03.11.2022 Gazette 2022/44)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME
	Designated Validation States:
	KH MA MD TN

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Priority:

27.04.2021 US 202163180646 P

(71)	Applicant: Adverum Biotechnologies, Inc.
	Redwood City, CA 94063 (US)

(72)	Inventors:
	CLARK, Julie Redwood City, CA 94063 (US) WHITCUP, Scott Redwood City, CA 94063 (US) TURPCU, Adam Redwood City, CA 94063 (US)

(74)	Representative: EIP
	Fairfax House 15 Fulwood Place London WC1V 6HU London WC1V 6HU (GB)

(54)	METHODS OF TREATING OCULAR DISEASES USING AAV2 VARIANTS ENCODING AFLIBERCEPT