(19)
(11) EP 4 333 844 A1

(12)

(43) Date of publication:
13.03.2024 Bulletin 2024/11

(21) Application number: 22799725.1

(22) Date of filing: 06.05.2022
(51) International Patent Classification (IPC): 
A61K 31/44(2006.01)
A61K 31/4965(2006.01)
A61K 31/50(2006.01)
A61K 31/397(2006.01)
A61K 31/5375(2006.01)
C07D 241/20(2006.01)
C07D 237/20(2006.01)
C07D 205/04(2006.01)
C07C 235/22(2006.01)
C07C 243/28(2006.01)
A61P 25/28(2006.01)
 A61K 31/165(2006.01)
A61K 31/505(2006.01)
A61K 31/42(2006.01)
A61K 31/40(2006.01)
C07D 213/75(2006.01)
C07D 261/14(2006.01)
C07D 239/42(2006.01)
C07D 295/185(2006.01)
C07C 235/06(2006.01)
C07C 235/08(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/397; A61K 31/40; A61K 31/42; A61K 31/44; A61K 31/4965; A61K 31/50; A61K 31/505; A61K 31/5375; A61P 25/28; C07C 235/22; C07C 243/28; C07D 205/04; C07D 213/75; C07D 237/20; C07D 239/42; C07D 241/20; C07D 261/14; C07D 295/185; C07D 237/22; C07C 235/20; C07C 2601/02; C07C 2601/14; C07C 2601/04; A61K 45/06; A61K 31/165; A61K 31/18
 
C-Sets:
  1. A61K 31/50, A61K 2300/00;
  2. A61K 31/165, A61K 2300/00;
  3. A61K 31/505, A61K 2300/00;
  4. A61K 31/40, A61K 2300/00;
  5. A61K 31/397, A61K 2300/00;
  6. A61K 31/18, A61K 2300/00;
  7. A61K 31/44, A61K 2300/00;
  8. A61K 31/5375, A61K 2300/00;
  9. A61K 31/4965, A61K 2300/00;
  10. A61K 31/42, A61K 2300/00;
(86) International application number:
PCT/US2022/028187
(87) International publication number:
WO 2022/236133 (10.11.2022 Gazette 2022/45)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 06.05.2021 US 202163185254 P
02.11.2021 US 202163274856 P

(71) Applicant: Autobahn Therapeutics, Inc.
San Diego CA 92121 (US)

(72) Inventors:
  • STEARNS, Brian Andrew
    San Diego, California 92121 (US)
  • BACCEI, Jill Melissa
    San Diego, California 92121 (US)
  • HARRIS, Jason Randall
    San Diego, California 92121 (US)

(74) Representative: Mewburn Ellis LLP 
Aurora Building Counterslip
Bristol BS1 6BX
Bristol BS1 6BX (GB)

   


(54) FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS