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EP 4 333 978 A1

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(43) Date of publication: 13.03.2024 Bulletin 2024/11 (21) Application number: 22724122.1 (22) Date of filing: 04.05.2022

(51) International Patent Classification (IPC):  A61N 5/10(2006.01) A61K 41/00(2020.01) A61K 51/12(2006.01) A61K 9/16(2006.01) A61K 49/22(2006.01) A61M 37/00(2006.01) (52) Cooperative Patent Classification (CPC): A61N 5/1007; A61N 5/1027; A61N 2005/1024; A61N 2007/0039; A61K 41/00; A61K 51/1244; A61N 7/00; A61N 2007/0065; A61N 2007/0095; A61K 9/0009; A61K 9/1611 (86) International application number: PCT/GB2022/051126 (87) International publication number: WO 2022/234266 (10.11.2022 Gazette 2022/45)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 05.05.2021 GB 202106412 (71) Applicants: Biocompatibles UK Limited FarnhamSurrey GU9 8QL (GB) Oxford University Innovation Limited Oxford, OX2 0JB (GB)	(72) Inventors: VINCE, Jonathan James Billingshurst West Sussex RH14 0NN (GB) STRIDE, Eleanor Phoebe Jane Oxford Oxfordshire OX2 6UG (GB) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)