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EP 4 334 310 A1

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(43) Date of publication: 13.03.2024 Bulletin 2024/11 (21) Application number: 22725155.0 (22) Date of filing: 06.05.2022

(51) International Patent Classification (IPC):  C07D 405/14(2006.01) C07D 487/10(2006.01) A61P 35/02(2006.01) A61K 31/53(2006.01) C07D 471/10(2006.01) A61P 35/00(2006.01) A61P 3/10(2006.01) A61K 31/407(2006.01) (52) Cooperative Patent Classification (CPC): C07D 487/10; C07D 471/10; C07D 405/14; A61P 35/00; A61P 35/02; A61P 3/10 (86) International application number: PCT/CN2022/091065 (87) International publication number: WO 2022/237626 (17.11.2022 Gazette 2022/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 08.05.2021 WO PCT/CN2021/092256 (71) Applicant: JANSSEN Pharmaceutica NV 2340 Beerse (BE)

(72) Inventors: QUEROLLE, Olivier Alexis Georges 92787 Issy-les Moulineaux Cedex 9 (FR) DAI, Xuedong Shanghai 200233 (CN) CAI, Wei Shanghai 200233 (CN) THURING, Johannes Wilhelmus J. 2340 Beerse (BE) FANG, Lichao Shanghai 200233 (CN) LI, Ming Shanghai 200233 (CN) LIU, Lianzhu Shanghai 200233 (CN) LIU, Yingtao Shanghai 200233 (CN) QIN, Luoheng Shanghai 200233 (CN) WU, Jianping Shanghai 200233 (CN) XU, Yanping Shanghai 200233 (CN) ANGIBAUD, Patrick René 92787 Issy-les Moulineaux Cedex 9 (FR) COLOMBEL, Hélène France Solange 92787 Issy-les Moulineaux Cedex 9 (FR) PILATTE, Isabelle Noëlle Constance 92787 Issy-les Moulineaux Cedex 9 (FR) PONCELET, Virginie Sophie 92787 Issy-les Moulineaux Cedex 9 (FR) KRAMER, Carsten Sven 2340 Beerse (BE) PANDE, Vineet 2340 Beerse (BE) (74) Representative: Lenaerts, Philip  Johnson & Johnson Patent Law Department Turnhoutseweg 30 2340 Beerse 2340 Beerse (BE)