(19)
(11) EP 4 337 259 A1

(12)

(43) Date of publication:
20.03.2024 Bulletin 2024/12

(21) Application number: 21726997.6

(22) Date of filing: 14.05.2021
(51) International Patent Classification (IPC): 
A61K 47/55(2017.01)
C07D 417/14(2006.01)
 A61P 25/28(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 47/55; A61P 25/28; A61K 47/545
(86) International application number:
PCT/IB2021/054167
(87) International publication number:
WO 2022/238737 (17.11.2022 Gazette 2022/46)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(71) Applicant: Aprinoia Therapeutics Limited
Wanchai (HK)

(72) Inventors:
  • JANG, Ming-Kuei
    Taipei City, 11503 (TW)
  • TEMPEST, Paul
    Taipei (TW)
  • LIN, Yih-Shyan
    Kaohsiung City, 830 (TW)

(74) Representative: Lavoix 
Bayerstraße 83
80335 München
80335 München (DE)

   


(54) COMPOUNDS FOR DEGRADING ALPHA-SYNUCLEIN AGGREGATES AND USES THEREOF