(19)

(11)

EP 4 351 572 A1

(12)

(43) Date of publication: 17.04.2024 Bulletin 2024/16 (21) Application number: 22733921.5 (22) Date of filing: 10.06.2022

(51) International Patent Classification (IPC):  A61K 31/4184(2006.01) A61K 31/704(2006.01) A61P 35/00(2006.01) A61K 9/00(2006.01) A61K 9/20(2006.01) A61K 9/51(2006.01) A61K 31/7032(2006.01) A61K 45/06(2006.01) A61K 9/107(2006.01) A61K 9/127(2006.01) A61K 9/14(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/7032; A61K 31/704; A61K 31/4184; A61K 45/06; A61P 35/00; A61K 9/1075; A61K 9/513; A61K 9/5123; A61K 9/127; A61K 9/2004; A61K 9/0019; A61K 9/141; A61K 9/0095; A61K 31/155   C-Sets: A61K 31/7032, A61K 2300/00; A61K 31/704, A61K 2300/00; A61K 31/4184, A61K 2300/00; A61K 31/155, A61K 2300/00; (86) International application number: PCT/EP2022/065907 (87) International publication number: WO 2022/258838 (15.12.2022 Gazette 2022/50)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.06.2021 EP 21178961 (71) Applicant: RainCastle bio. Limited London WC2H 9JQ (GB)	(72) Inventor: M A KH M ALENEZE, Yousef Kuwait (KW) (74) Representative: Thoma, Michael  Lorenz Seidler Gossel Rechtsanwälte Patentanwälte Partnerschaft mbB Widenmayerstraße 2380538 München Widenmayerstraße 2380538 München (DE)