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EP 4 355 361 A1

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(43) Date of publication: 24.04.2024 Bulletin 2024/17 (21) Application number: 22823723.6 (22) Date of filing: 14.06.2022

(51) International Patent Classification (IPC):  A61K 39/29(2006.01) A61P 37/04(2006.01) C07K 19/00(2006.01) C12N 15/62(2006.01) A61P 31/14(2006.01) C07K 14/18(2006.01) C12N 15/51(2006.01) C12N 15/85(2006.01) (52) Cooperative Patent Classification (CPC): A61P 31/14; A61P 37/04; C12N 15/62; C07K 14/005; C12N 2770/24222; C12N 2770/24234; C12N 2840/203; C12N 15/88; A61K 9/1272; A61K 9/5115; A61K 2039/51; A61K 39/12; A61K 2039/545; A61K 2039/575; A61K 2039/70; A61K 2039/55555 (86) International application number: PCT/CA2022/050946 (87) International publication number: WO 2022/261758 (22.12.2022 Gazette 2022/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 15.06.2021 US 202163210722 P 21.06.2021 US 202163212877 P 24.03.2022 US 202263323434 P 25.05.2022 US 202263345799 P (71) Applicant: Aurora Vaccines, Inc. Calgary, Alberta T2P 3N9 (CA)

(72) Inventors: HOUGHTON, Michael Calgary, Alberta T2P 3N9 (CA) LAW, John L. Calgary, Alberta T2P 3N9 (CA) LANDI, Abdolamir Calgary, Alberta T2P 3N9 (CA) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)