(19)

(11)

EP 4 355 751 A1

(12)

(43) Date of publication: 24.04.2024 Bulletin 2024/17 (21) Application number: 22740705.3 (22) Date of filing: 13.06.2022

(51) International Patent Classification (IPC):  C07D 519/00(2006.01) A61K 31/519(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07D 519/00; A61P 35/00 (86) International application number: PCT/US2022/033305 (87) International publication number: WO 2022/266015 (22.12.2022 Gazette 2022/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 14.06.2021 US 202163210474 P 17.12.2021 US 202163291320 P 23.02.2022 US 202263313132 P (71) Applicant: Kumquat Biosciences Inc. San Diego, CA 92121 (US)	(72) Inventors: LI, Liansheng San Diego, CA 92121 (US) ZHU, Xiuwen San Diego, CA 92121 (US) REN, Pingda San Diego, CA 92121 (US) LIU, Yi San Diego, CA 92121 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)