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(11)

EP 4 359 383 A1

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(43) Date of publication: 01.05.2024 Bulletin 2024/18 (21) Application number: 22735858.7 (22) Date of filing: 21.06.2022

(51) International Patent Classification (IPC):  C07D 207/335(2006.01) A61P 9/00(2006.01) A61P 29/00(2006.01) A61K 31/402(2006.01) A61P 13/00(2006.01) A61P 31/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/0095; A61K 9/2009; A61K 9/2013; A61K 9/2027; A61K 9/2054; A61K 9/2059; A61K 9/2846; A61K 31/402; A61P 9/10; A61P 11/00; A61P 17/00; A61P 17/06; A61P 19/02; A61P 29/00; A61P 31/12; A61P 35/00; A61P 35/02; A61P 37/06; A61P 43/00; C07C 53/06; C07C 53/10; C07C 55/10; C07C 55/12; C07C 55/14; C07C 59/08; C07C 59/347; C07C 59/50; C07C 233/83; C07C 309/29; C07D 207/335; A61P 9/00; A61P 13/00; A61P 31/00 (86) International application number: PCT/EP2022/066884 (87) International publication number: WO 2022/268814 (29.12.2022 Gazette 2022/52)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 21.06.2021 EP 21180708 21.06.2021 EP 21180702 23.11.2021 EP 21209855 (71) Applicant: SynAct Pharma ApS 2840 Holte (DK)	(72) Inventors: BOESEN, Thomas 2100 Copenhagen Ø (DK) JONASSEN, Thomas Engelbrecht Nordkild 2840 Holte (DK) REECE, Hayley Ann Dalkeith EH22 2AL (GB) KELK, Natalie Louise Edinburgh EH28 8SF (GB) TURNER, Alice Jane Edinburgh EH10 6DS (GB) MCLELLAN, Ross Glasgow G53 7WU (GB) (74) Representative: Høiberg P/S  Adelgade 12 1304 Copenhagen K 1304 Copenhagen K (DK)