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EP 4 363 113 A1

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(43) Date of publication: 08.05.2024 Bulletin 2024/19 (21) Application number: 22832343.2 (22) Date of filing: 29.06.2022

(51) International Patent Classification (IPC):  B01L 3/00(2006.01) C12M 3/00(2006.01) C12N 5/071(2010.01) C12M 1/00(2006.01) G01N 33/50(2006.01) F16K 99/00(2006.01) (52) Cooperative Patent Classification (CPC): B33Y 80/00; B01L 3/502761; B01L 2300/0877; B01L 2300/087; B01L 2300/0887; B01L 3/502715; C12M 21/08; C12M 23/16; C12M 23/42 (86) International application number: PCT/IL2022/050698 (87) International publication number: WO 2023/275871 (05.01.2023 Gazette 2023/01)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.07.2021 US 202163217356 P (71) Applicant: Ramot at Tel-Aviv University Ltd. Tel-Aviv 6139201 (IL)	(72) Inventors: MAOZ, Ben Meir 6139201 Tel Aviv (IL) HERLAND, Anna 6139201 Tel Aviv (IL) DIVALD, Shay 6139201 Tel Aviv (IL) OLIEL, Yuval 6139201 Tel Aviv (IL) (74) Representative: Kancelaria Eupatent.pl Sp. z.o.o  Ul. Kilinskiego 185 90-348 Lodz 90-348 Lodz (PL)