(19)
(11) EP 4 363 595 A1

(12)

(43) Date of publication:
08.05.2024 Bulletin 2024/19

(21) Application number: 22832293.9

(22) Date of filing: 28.06.2022
(51) International Patent Classification (IPC): 
C12N 15/85(2006.01)
C12N 15/10(2006.01)
C12N 15/90(2006.01)
C12N 5/10(2006.01)
C12N 15/67(2006.01)
C12P 21/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 15/63; C07K 16/32; C12N 15/85; C12N 2820/60; C12N 15/907
(86) International application number:
PCT/IB2022/055963
(87) International publication number:
WO 2023/275720 (05.01.2023 Gazette 2023/01)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 28.06.2021 US 202163215876 P
12.10.2021 US 202163254997 P

(71) Applicant: Inpamac Biotech Canada Inc.
Charlottetown, Prince Edward Island C1A 2A7 (CA)

(72) Inventor:
  • KATONA, Laszlo Robert
    6723 Szeged (HU)

(74) Representative: Bartle Read 
Liverpool Science Park 131 Mount Pleasant
Liverpool L3 5TF
Liverpool L3 5TF (GB)

   


(54) COMPOSITIONS, CONSTRUCTS, CELLS AND METHODS FOR INCREASED RECOMBINANT PROTEIN EXPRESSION BY SITE-SPECIFIC INTEGRATION