(19)
(11) EP 4 371 472 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
03.07.2024 Bulletin 2024/27

(43) Date of publication A2:
22.05.2024 Bulletin 2024/21

(21) Application number: 23205172.2

(22) Date of filing: 23.10.2023
(51) International Patent Classification (IPC): 
A61B 5/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61B 5/0071; A61B 5/0077; A61B 5/0084; A61B 5/742; A61B 5/0035
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 15.11.2022 US 202263425402 P

(71) Applicant: Quest Photonic Devices B.V.
1771 SR Wieringerwerf (NL)

(72) Inventors:
  • HOVELING, Richelle Johanna Maria
    1623 JA Hoorn (NL)
  • MEESTER, Richard Johannes Cornelis
    1771 DA Wieringerwerf (NL)

(74) Representative: Seemann & Partner Patentanwälte mbB 
Raboisen 6
20095 Hamburg
20095 Hamburg (DE)

   


(54) METHOD OF MEASURING A FLUORESCENCE SIGNAL, DETERMINING A PEAK FREQUENCY MAP AND PROVIDING A RISK PREDICTION VALUE, IMAGE CAPTURING AND PROCESSING DEVICE


(57) An image capturing and processing device 2 configured to measure a fluorescence signal in a tissue of a body part 4 and to image a surface of the body part. The device 2 comprising a fluorescence imaging unit 22 configured to capture a fluorescence image 7 and a visible light imaging unit 24 configured to capture a visible light image 5. The fluorescence imaging unit 22 is further configured to capture a time sequence of fluorescence images 7. A peak frequency map unit 60 is configured to determine a peak frequency map for an area of interest in the fluorescence images by analyzing the time sequence of fluorescence images 7. The analysis comprising: determining a time-dependent intensity curve, identifying peaks in the time-dependent intensity curve and determining a frequency of the identified peaks and/or a maximum high of the identified peaks, generating a graphic representation of the determined frequency and/or maximum high and including the same in the peak frequency map. An output unit is configured to output the peak frequency map together with the visible light image 5 and/or the fluorescence image 7.







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