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EP 4 376 856 A1

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(43) Date of publication: 05.06.2024 Bulletin 2024/23 (21) Application number: 22850033.6 (22) Date of filing: 20.04.2022

(51) International Patent Classification (IPC):  A61K 35/17(2015.01) A61K 39/395(2006.01) A61K 51/10(2006.01) A61K 39/00(2006.01) A61K 47/68(2017.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 2317/24; C07K 16/2803; C07K 16/30; C07K 16/32; C07K 2317/76; A61K 2039/507; A61K 51/1093; A61K 51/1027; A61K 51/1096; A61K 51/1045; A61K 51/1051; A61K 35/17; A61K 39/00 (86) International application number: PCT/US2022/025655 (87) International publication number: WO 2023/009189 (02.02.2023 Gazette 2023/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 28.07.2021 US 202163226699 P 30.09.2021 US 202163250725 P 22.10.2021 WO PCT/US2021/056259 23.03.2022 US 202217702648 (71) Applicant: Actinium Pharmaceuticals, Inc. New York, NY 10017 (US)

(72) Inventors: LUDWIG, Dale L. ROCKAWAY, New Jersey 07866 (US) SETH, Sandesh New York, New York 10128 (US) DIAMOND, Paul FORT LEE, New Jersey 07024 (US) (74) Representative: Dentons Patent Solutions Rechtsanwaltsgesellschaft mbH  Jungfernturmstraße 2 80333 München 80333 München (DE)