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EP 4 380 684 A1

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(43) Date of publication: 12.06.2024 Bulletin 2024/24 (21) Application number: 22741379.6 (22) Date of filing: 24.06.2022

(51) International Patent Classification (IPC):  A61P 1/04(2006.01) A61K 38/17(2006.01) A61P 1/00(2006.01) C12Q 1/04(2006.01) A61P 13/12(2006.01) A61P 35/00(2006.01) A61K 38/00(2006.01) A61P 29/00(2006.01) A61P 3/00(2006.01) A61P 9/00(2006.01) A61P 25/00(2006.01) A61P 37/02(2006.01) (52) Cooperative Patent Classification (CPC): A61P 1/04; A61P 29/00; A61P 1/00; A61P 3/00; A61P 25/00; A61P 13/12; A61P 9/00; A61P 37/02; A61P 35/00; G01N 2333/4727; A61K 38/1738; G01N 2800/06 (86) International application number: PCT/IB2022/055889 (87) International publication number: WO 2023/012540 (09.02.2023 Gazette 2023/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 04.08.2021 IT 202100021146 (71) Applicants: Genes S.r.l. 00187 Roma (IT) Romano Spica, Vincenzo 00136 Rome (IT)	(72) Inventors: MICHETTI, Fabrizio 00186 Roma (IT) ROMANO SPICA, Vincenzo 00136 Roma (IT) (74) Representative: Cavattoni, Raimondi & Luppi Srl  Viale dei Parioli, 160 00197 Rome 00197 Rome (IT)