(19)
(11) EP 4 381 512 A1

(12)

(43) Date of publication:
12.06.2024 Bulletin 2024/24

(21) Application number: 22761904.6

(22) Date of filing: 04.08.2022
(51) International Patent Classification (IPC): 
G16B 20/20(2019.01)
G16B 40/20(2019.01)
(52) Cooperative Patent Classification (CPC):
G16B 20/20; G16B 40/20
(86) International application number:
PCT/US2022/074523
(87) International publication number:
WO 2023/015244 (09.02.2023 Gazette 2023/06)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 05.08.2021 US 202163229797 P

(71) Applicant: Grail, LLC
Menlo Park, CA 94025 (US)

(72) Inventors:
  • SINGH, Pranav Parmjit
    Menlo Park, California 94025 (US)
  • VENN, Oliver, Claude
    Menlo Park, California 94025 (US)

(74) Representative: Murgitroyd & Company 
165-169 Scotland Street
Glasgow G5 8PL
Glasgow G5 8PL (GB)

   


(54) SOMATIC VARIANT COOCCURRENCE WITH ABNORMALLY METHYLATED FRAGMENTS