(19)

(11)

EP 4 384 201 A2

(12)

(88) Date of publication A3: 28.09.2023 (43) Date of publication: 19.06.2024 Bulletin 2024/25 (21) Application number: 22856825.9 (22) Date of filing: 11.08.2022

(51) International Patent Classification (IPC):  A61K 38/17(2006.01) C07K 14/715(2006.01) C07K 19/00(2006.01) A61P 37/06(2006.01) C07K 16/46(2006.01) (52) Cooperative Patent Classification (CPC): A61K 47/68; C07K 14/70578; A61K 38/177; C07K 2319/30; A61P 37/06 (86) International application number: PCT/US2022/074868 (87) International publication number: WO 2023/019223 (16.02.2023 Gazette 2023/07)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.08.2021 US 202163232124 P (71) Applicant: Akso Biopharmaceutical, Inc. Los Angeles, CA 90067 (US)	(72) Inventors: GIACCIA, Amato J. Oxford, OX2 9AU (GB) MIAO, Yu Sunnyvale, California 94085 (US) ZHANG, Xin Eric Newport Coast, California 92657 (US) (74) Representative: AWA Sweden AB  Box 5117 200 71 Malmö 200 71 Malmö (SE)