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EP 4 384 213 A1

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(43) Date of publication: 19.06.2024 Bulletin 2024/25 (21) Application number: 23818271.1 (22) Date of filing: 01.11.2023

(51) International Patent Classification (IPC):  A61K 39/12(2006.01) A61P 31/14(2006.01) (52) Cooperative Patent Classification (CPC): A61K 39/12; A61P 31/14; C12N 2770/20034; A61K 2039/55522; A61K 2039/572; A61K 2039/575; A61K 2039/543 (86) International application number: PCT/CN2023/129016 (87) International publication number: WO 2024/094050 (10.05.2024 Gazette 2024/19)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 02.11.2022 US 202263382009 P 06.02.2023 US 202318165286 27.02.2023 CN 202310170595 (71) Applicant: Centre For Virology, Vaccinology and Therapeutics Limited Pak Shek Kok, N.T. (HK)

(72) Inventor: KOK, Kin Hang Kwan O (HK) (74) Representative: CMS Cameron McKenna Nabarro Olswang LLP  Cannon Place 78 Cannon Street London EC4N 6AF London EC4N 6AF (GB)