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EP 4 388 131 A1

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(43) Date of publication: 26.06.2024 Bulletin 2024/26 (21) Application number: 22859206.9 (22) Date of filing: 19.08.2022

(51) International Patent Classification (IPC):  C12Q 1/6841(2018.01) C12Q 1/6804(2018.01) G01N 33/53(2006.01) G01N 33/543(2006.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6841; C12Q 1/6804; C12Q 1/6883; C12Q 2600/158; G01N 33/5308   C-Sets: C12Q 1/6841, C12Q 2563/149, C12Q 2563/179; C12Q 1/6804, C12Q 2563/149, C12Q 2563/179; (86) International application number: PCT/US2022/040859 (87) International publication number: WO 2023/023308 (23.02.2023 Gazette 2023/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 20.08.2021 US 202163235304 P (71) Applicant: 13.8, Inc. Palo Alto, CA 94303 (US)	(72) Inventors: CHANG, Christina Palo Alto, California 94303 (US) FODOR, Stephen P. A. Palo Alto, California 94303 (US) FAN, Hei Mun Christina Palo Alto, California 94303 (US) SHAHRAVAN, Anaram Palo Alto, California 94303 (US) LEVINE, Jay Palo Alto, California 94303 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)