(19)
(11) EP 4 395 775 A1

(12)

(43) Date of publication:
10.07.2024 Bulletin 2024/28

(21) Application number: 22769880.0

(22) Date of filing: 30.08.2022
(51) International Patent Classification (IPC): 
A61K 31/4355(2006.01)
A61P 35/04(2006.01)
A61P 43/00(2006.01)
A61P 35/00(2006.01)
A61K 45/06(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/4355; A61P 35/00; A61P 35/04; A61K 45/06; A61P 43/00
 
C-Sets:
A61K 31/4355, A61K 2300/00;
(86) International application number:
PCT/EP2022/025399
(87) International publication number:
WO 2023/030687 (09.03.2023 Gazette 2023/10)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 01.09.2021 EP 21020440

(71) Applicant: KHR Biotec GmbH
21037 Hamburg (DE)

(72) Inventor:
  • RAJALINGAM, Krishnaraj
    55118 Nieder-Olm (DE)

(74) Representative: Zellentin & Partner mbB Patentanwälte 
Rubensstraße 30
67061 Ludwigshafen
67061 Ludwigshafen (DE)

   


(54) CYCLOPENTA[4,5]FURO[3,2-C]PYRIDINE DERIVATIVES AS RAS INHIBITORS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES OR GENETIC DISORDERS