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(11)

EP 4 396 216 A1

(12)

(43) Date of publication: 10.07.2024 Bulletin 2024/28 (21) Application number: 22777932.9 (22) Date of filing: 02.09.2022

(51) International Patent Classification (IPC):  C07K 14/725(2006.01) A61K 39/00(2006.01) C07K 14/705(2006.01) (52) Cooperative Patent Classification (CPC): C07K 2317/622; C07K 2317/74; C07K 14/7051; C07K 14/70521; C07K 14/70517; A61K 39/0008; C07K 2319/03; C07K 2319/33; A61K 39/46433; A61K 39/4631; A61K 39/4621; A61K 2239/38; A61K 2239/31; A61K 39/4611 (86) International application number: PCT/US2022/075956 (87) International publication number: WO 2023/035002 (09.03.2023 Gazette 2023/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 03.09.2021 US 202163240626 P (71) Applicant: Sangamo Therapeutics, Inc. Richmond, CA 94804 (US)	(72) Inventors: ABEL, Tobias Brisbane, California 94005 (US) DE LA ROSA, Maurus Brisbane, California 94005 (US) DUMONT, Céline Brisbane, California 94005 (US) FENARD, David Brisbane, California 94005 (US) FRIKECHE, Jihane Brisbane, California 94005 (US) (74) Representative: FRKelly  Waterways House Grand Canal Quay Dublin D02 PD39 Dublin D02 PD39 (IE)