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EP 4 404 857 A1

(12)

(43) Date of publication: 31.07.2024 Bulletin 2024/31 (21) Application number: 22870831.9 (22) Date of filing: 19.09.2022

(51) International Patent Classification (IPC):  A61B 18/14(2006.01) A61K 39/395(2006.01) (52) Cooperative Patent Classification (CPC): A61K 2039/505; A61K 39/39541; A61P 35/00; C07K 16/2818; A61P 35/04; C07K 2317/76; A61B 2018/00577; A61B 18/1492; A61B 2018/1425   C-Sets: A61K 39/39541, A61K 2300/00; (86) International application number: PCT/US2022/044021 (87) International publication number: WO 2023/044124 (23.03.2023 Gazette 2023/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 20.09.2021 US 202163246239 P 16.12.2021 US 202163290529 P 22.03.2022 US 202263322319 P 13.06.2022 US 202263351562 P (71) Applicant: Galvanize Therapeutics, Inc. Redwood City, CA 94065 (US)

(72) Inventors: O'BRIEN, Timothy, J. Redwood City, CA 94065 (US) KRIMSKY, William, S. Redwood City, CA 94065 (US) SILVESTRINI, Matthew, T. Redwood City, CA 94065 (US) PASTORI, Chiara Redwood City, CA 94065 (US) NEAL, Robert, E., II Redwood City, CA 94065 (US) WALDSTREICHER, Jonathan, R. Redwood City, CA 94065 (US) (74) Representative: Clark, Jane Anne et al Mathys & Squire The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)