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EP 4 408 465 A1

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(43) Date of publication: 07.08.2024 Bulletin 2024/32 (21) Application number: 22812846.8 (22) Date of filing: 27.09.2022

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61P 37/00(2006.01) A61K 39/00(2006.01) A61P 17/00(2006.01) C07K 16/28(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2866; A61K 39/395; A61P 17/00; A61P 37/00; A61K 2039/505; A61K 2039/545 (86) International application number: PCT/SG2022/050694 (87) International publication number: WO 2023/048651 (30.03.2023 Gazette 2023/13)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 27.09.2021 SG 10202110688T 27.09.2021 SG 10202110690S 27.09.2021 SG 10202110730R 29.10.2021 SG 10202112085U 22.02.2022 SG 10202201722U 01.03.2022 WO PCT/SG2022/050102 01.03.2022 WO PCT/SG2022/050103 25.03.2022 US 202263323961 P 18.05.2022 SG 10202205222Q 26.08.2022 SG 10202250837V 06.09.2022 SG 10202250923N 06.09.2022 US 202217929824 06.09.2022 US 202217929874 15.09.2022 US 202263375736 P 22.09.2022 US 202263376663 P (71) Applicant: ASLAN Pharmaceuticals Pte Ltd Singapore 039190 (SG)

(72) Inventors: WARD, Alison Singapore 039190 (SG) CEVIKBAS, Ferda Palo Alto, California 94303 (US) VEVERKA, Karen Singapore 039190 (SG) (74) Representative: Sterling IP  Orion House Bessemer Road Welwyn Garden City AL7 1HH Welwyn Garden City AL7 1HH (GB)