(19)
(11) EP 4 408 824 A1

(12)

(43) Date of publication:
07.08.2024 Bulletin 2024/32

(21) Application number: 22801349.6

(22) Date of filing: 30.09.2022
(51) International Patent Classification (IPC): 
C07D 215/18(2006.01)
C07D 471/04(2006.01)
A61K 31/4704(2006.01)
A61K 31/4375(2006.01)
 C07D 215/22(2006.01)
A61K 31/14(2006.01)
A61K 31/437(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 471/04; C07D 215/18; C07D 215/22; C07D 215/227; C07D 215/233; A61P 31/14
(86) International application number:
PCT/EP2022/077414
(87) International publication number:
WO 2023/052638 (06.04.2023 Gazette 2023/14)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 30.09.2021 EP 21306368

(71) Applicants:
  • Qubit Pharmaceuticals
    75014 Paris (FR)
  • Centre National de la Recherche Scientifique
    75016 Paris (FR)
  • SORBONNE UNIVERSITE
    75006 Paris (FR)

(72) Inventors:
  • DEPLANO, Alessandro
    37121 VERONA (IT)
  • SABBADIN, Davide
    4058 BASEL (CH)
  • PIQUEMAL, Jean-Philip
    75052 PARIS cedex (FR)
  • CUZZOLIN, Alberto
    43123 PARMA (IT)
  • LAGARDERE, Louis
    75011 PARIS (FR)
  • EL KHOURY, Lea
    75014 PARIS (FR)
  • JING, Francis
    MEMPHIS, Tennessee 38105 (US)

(74) Representative: A.P.I. Conseil 
Technopôle Hélioparc 4, rue Jules Ferry
64000 Pau
64000 Pau (FR)

   


(54) NOVEL INHIBITORS OF CORONAVIRUSES 3-CHYMOTRYPSIN-LIKE PROTEASE