(19)
(11) EP 4 408 979 A1

(12)

(43) Date of publication:
07.08.2024 Bulletin 2024/32

(21) Application number: 21810715.9

(22) Date of filing: 30.09.2021
(51) International Patent Classification (IPC): 
C12N 5/0775(2010.01)
C07K 14/47(2006.01)
 C12Q 1/6881(2018.01)
G01N 33/50(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 5/0667; C12Q 1/6881; C07K 14/47; G01N 33/574; C12Q 1/6886; C12Q 2600/158
(86) International application number:
PCT/IB2021/058990
(87) International publication number:
WO 2023/052820 (06.04.2023 Gazette 2023/14)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(71) Applicant: Polski Bank Komórek Macierzystych S.A.
00-867 Warszawa (PL)

(72) Inventors:
  • OLDAK, Tomasz
    05-200 Wo omin (PL)
  • KOLANOWSKI, Tomasz
    60-464 Pozna (PL)
  • STEPANIEC, Igor
    02-736 Warszawa (PL)
  • MACHAJ, Krzysztof
    02-791 Warszawa (PL)

(74) Representative: JWP Patent & Trademark Attorneys 
ul. Minska 75
03-828 Warszawa
03-828 Warszawa (PL)

   


(54) EXPRESSION ANALYSIS OF A SPECIFIC GENE POOL TO DETERMINE WHETHER THE POPULATION OF ADIPOSE TISSUE-DERIVED MESENCHYMAL CELLS (AT-MSC) SELECTED FOR CLINICAL APPLICATION CAN UNDERGO A TRANSFORMATION INTO NEOPLASTIC CELLS