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(11)

EP 4 412 636 A2

(12)

(88) Date of publication A3: 03.08.2023 (43) Date of publication: 14.08.2024 Bulletin 2024/33 (21) Application number: 22859187.1 (22) Date of filing: 12.09.2022

(51) International Patent Classification (IPC):  A61K 38/21(2006.01) C07K 16/28(2006.01) A61P 31/12(2006.01) C07K 14/56(2006.01) A61K 47/68(2017.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/56; C07K 2319/33; A61K 38/00; C07K 2317/76; C07K 16/2827; A61K 2039/505 (86) International application number: PCT/US2022/040807 (87) International publication number: WO 2023/023283 (23.02.2023 Gazette 2023/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.06.2022 US 202263347871 P (71) Applicant: REMD Biotherapeutics, Inc. Camarillo, California 93012 (US)	(72) Inventors: YAN, Hai Thousand Oaks, CA 91320 (US) WANG, Wuyi Newbury Park, CA 91320 (US) STEWARD, Kristopher Newbury Park, CA 91320 (US) (74) Representative: Boynton, Juliette Alice et al Schlich 9 St. Catherine's Road Littlehampton, West Sussex BN17 5HS Littlehampton, West Sussex BN17 5HS (GB)