(19)

(11)

EP 4 413 001 A1

(12)

(43) Date of publication: 14.08.2024 Bulletin 2024/33 (21) Application number: 22802014.5 (22) Date of filing: 03.10.2022

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) A61P 35/00(2006.01) A61K 31/437(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/04 (86) International application number: PCT/EP2022/077470 (87) International publication number: WO 2023/057389 (13.04.2023 Gazette 2023/15)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 04.10.2021 US 202163251916 P 26.10.2021 EP 21204879 22.12.2021 EP 21217026 21.03.2022 US 202263321955 P 20.07.2022 US 202263390855 P (71) Applicant: FoRx Therapeutics AG 4056 Basel (CH)

(72) Inventors: LUECKING, Ulrich 10317 Berlin (DE) GOUTOPOULOS, Andreas Boston, Massachusetts 02116 (US) TIAN, Jin WuHan East Lake High-tech Development Zone Hubei, 430075 (CN) SOTIRIOU, Sotirios 4153 Reinach BL (CH) IACOVINO, Luca 4310 Rheinfelden (CH) FREUDENMANN, Alena 4125 Riehen (CH) QUEROLLE, Olivier 68300 Saint Louis (FR) (74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB  Siebertstraße 3 81675 München 81675 München (DE)