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(11)

EP 4 419 551 A1

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(43) Date of publication: 28.08.2024 Bulletin 2024/35 (21) Application number: 22813018.3 (22) Date of filing: 21.10.2022

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) A61P 25/28(2006.01) A61K 39/395(2006.01) A61K 31/454(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/18; C07K 2317/24; C07K 2317/92; A61K 2039/505; A61K 2039/54; A61K 2039/545; A61K 39/3955; A61P 25/28; A61K 31/454   C-Sets: A61K 39/3955, A61K 2300/00; A61K 31/454, A61K 2300/00; (86) International application number: PCT/US2022/078475 (87) International publication number: WO 2023/070064 (27.04.2023 Gazette 2023/17)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 22.10.2021 US 202163270820 P (71) Applicant: Eli Lilly and Company Indianapolis, IN 46285 (US)

(72) Inventors: BIGLAN, Kevin Indianapolis, Indiana 46206-6288 (US) FLEISHER, Adam S. Indianapolis, Indiana 46206-6288 (US) MERGOTT, Dustin James Indianapolis, Indiana 46206-6288 (US) NUTHALL, Hugh N. Indianapolis, Indiana 46206-6288 (US) (74) Representative: Faggiani, Davide  Eli Lilly and Company Limited European Patent Operations 8 Arlington Square West Downshire Way Bracknell RG12 1PU Bracknell RG12 1PU (GB)