(19)

(11)

EP 4 422 679 A1

(12)

(43) Date of publication: 04.09.2024 Bulletin 2024/36 (21) Application number: 22888385.6 (22) Date of filing: 18.10.2022

(51) International Patent Classification (IPC):  A61K 39/12(2006.01) A61P 31/12(2006.01) C12N 7/00(2006.01) C07K 14/005(2006.01) C07K 16/10(2006.01) (52) Cooperative Patent Classification (CPC): A61K 39/12; C07K 14/005; C12N 2770/20034; A61P 31/14; A61K 2039/6031; A61K 2039/572; A61K 2039/55561; C12N 2770/20022; C07K 2319/00; C07K 2319/50; C07K 2319/10; C07K 14/70578; C07K 16/1003 (86) International application number: PCT/US2022/078297 (87) International publication number: WO 2023/076820 (04.05.2023 Gazette 2023/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 26.10.2021 US 202163271982 P 26.10.2021 US 202163271987 P (71) Applicant: Navicure Biopharmaceuticals Limited Apia City (WS)	(72) Inventor: WU, Chia-Mao Hsinchu, 300 (TW) (74) Representative: Gill, Siân Victoria et al Venner Shipley LLP 200 Aldersgate London EC1A 4HD London EC1A 4HD (GB)