(19)

(11)

EP 4 423 114 A1

(12)

(43) Date of publication: 04.09.2024 Bulletin 2024/36 (21) Application number: 22813179.3 (22) Date of filing: 29.10.2022

(51) International Patent Classification (IPC):  C07K 14/415(2006.01) C12N 15/82(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/415; C12N 15/8261 (86) International application number: PCT/EP2022/080314 (87) International publication number: WO 2023/073224 (04.05.2023 Gazette 2023/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 29.10.2021 LU 500809 20.07.2022 GB 202210616 (71) Applicant: JOHN INNES CENTRE Norwich, Norfolk NR4 7UH (GB)	(72) Inventor: CHARPENTIER, Myriam Norwich Norfolk NR2 3BP (GB) (74) Representative: Marks & Clerk LLP  15 Fetter Lane London EC4A 1BW London EC4A 1BW (GB)