(19)

(11)

EP 4 429 627 A1

(12)

(43) Date of publication: 18.09.2024 Bulletin 2024/38 (21) Application number: 22823262.5 (22) Date of filing: 09.11.2022

(51) International Patent Classification (IPC):  A61K 8/35(2006.01) A61K 8/46(2006.01) A61K 8/41(2006.01) A61Q 17/04(2006.01) (52) Cooperative Patent Classification (CPC): A61Q 17/04; A61K 8/35; A61K 8/415; A61K 8/466 (86) International application number: PCT/US2022/079573 (87) International publication number: WO 2023/086839 (19.05.2023 Gazette 2023/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 11.11.2021 US 202117524222 (71) Applicant: Curie Co. Inc. Durham, NC 27709 (US)	(72) Inventors: MILCZEK, Erika M. Durham, North Carolina 27709 (US) SHINDEL, William Durham, North Carolina 27709 (US) SZABADOS, Zsolt Durham, North Carolina 27709 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)