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EP 4 433 033 A1

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(43) Date of publication: 25.09.2024 Bulletin 2024/39 (21) Application number: 22818716.7 (22) Date of filing: 18.11.2022

(51) International Patent Classification (IPC):  A61K 9/20(2006.01) A61P 17/06(2006.01) C30B 7/14(2006.01) A61K 31/4035(2006.01) C30B 1/02(2006.01) C30B 29/54(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/4035; A61K 9/2054; A61K 9/2018; A61P 17/06; C30B 29/54; C30B 7/14 (86) International application number: PCT/EP2022/082426 (87) International publication number: WO 2023/089101 (25.05.2023 Gazette 2023/21)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 18.11.2021 EP 21209153 (71) Applicant: KRKA, d.d., Novo mesto 8000 Novo mesto (SI)

(72) Inventors: LORBEK, Gregor 8501 NOVO MESTO (SI) PAVLIN, Darja 8501 NOVO MESTO (SI) HOTKO, Anka 8501 NOVO MESTO (SI) KORASA, Klemen 8501 NOVO MESTO (SI) GOGNJAVEC, Tja a 8501 NOVO MESTO (SI) BEZEN EK, Jure 8501 NOVO MESTO (SI) BENKIC, Primo 8501 NOVO MESTO (SI) PU AVEC KIRAR, Eva 8501 NOVO MESTO (SI) (74) Representative: Hoefer & Partner Patentanwälte mbB  Pilgersheimer Straße 20 81543 München 81543 München (DE)