(19)

(11)

EP 4 433 613 A1

(12)

(43) Date of publication: 25.09.2024 Bulletin 2024/39 (21) Application number: 22835933.7 (22) Date of filing: 14.11.2022

(51) International Patent Classification (IPC):  C12Q 1/6886(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6886; C12Q 2600/156; C12Q 2600/158; C12Q 2600/118; C12Q 2600/112; C12Q 2600/106 (86) International application number: PCT/US2022/049833 (87) International publication number: WO 2023/086635 (19.05.2023 Gazette 2023/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 15.11.2021 US 202163279246 P 07.12.2021 US 202163286727 P (71) Applicant: VIR Biotechnology, Inc. San Francisco, CA 94158 (US)	(72) Inventors: MAHER, Michael Cyrus Riley San Francisco, California 94158 (US) SORIAGA, Leah B. San Francisco, California 94158 (US) TELENTI, Amalio San Francisco, California 94158 (US) (74) Representative: Elkington and Fife LLP  Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR Sevenoaks, Kent TN13 1XR (GB)