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(11)

EP 4 436 467 A1

(12)

(43) Date of publication: 02.10.2024 Bulletin 2024/40 (21) Application number: 22896821.0 (22) Date of filing: 22.11.2022

(51) International Patent Classification (IPC):  A61B 5/00(2006.01) G01N 33/53(2006.01) G01N 33/50(2006.01) C07K 14/47(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/745; A61B 5/055; A61B 5/0042; A61B 5/4064; G01N 33/6896; G01N 2800/52; G01N 2800/2871 (86) International application number: PCT/US2022/080374 (87) International publication number: WO 2023/092157 (25.05.2023 Gazette 2023/21)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 22.11.2021 US 202163282176 P 23.11.2021 US 202163282619 P (71) Applicant: Brainbox Solutions, Inc. Richmond, VA 23219 (US)	(72) Inventors: EDMONDS, Donna, J. Richmond, VA 23219 (US) VAN METER, Timothy, E. Richmond, VA 23219 (US) MIRSHAHI, Nazanin Richmond, VA 23219 (US) (74) Representative: Jacobi, Markus Alexander  Patentanwälte Isenbruck Bösl Hörschler PartG mbB Eastsite One Seckenheimer Landstrasse 4 68163 Mannheim 68163 Mannheim (DE)