(19)

(11)

EP 4 444 166 A2

(12)

(88) Date of publication A3: 28.09.2023 (43) Date of publication: 16.10.2024 Bulletin 2024/42 (21) Application number: 23729644.7 (22) Date of filing: 13.01.2023

(51) International Patent Classification (IPC):  A61B 5/024(2006.01) A61B 5/02(2006.01) G01N 21/59(2006.01) A61B 5/1455(2006.01) G01J 1/44(2006.01) (52) Cooperative Patent Classification (CPC): A61B 5/02125; A61B 5/02416; A61B 5/14532 (86) International application number: PCT/US2023/010739 (87) International publication number: WO 2023/108177 (15.06.2023 Gazette 2023/24)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 06.12.2021 US 202117543702 22.12.2021 US 202117523754 (71) Applicant: Quantum Biotek Inc. Atlanta, GA 30341 (US)	(72) Inventors: ANDROSCH, Astrid Atlanta, GA 30341 (US) YUAN, David Atlanta, GA 30341 (US) FRIDMAN, Vladimir Brooklyn, NY 11215 (US) (74) Representative: FRKelly  Waterways House Grand Canal Quay Dublin D02 PD39 Dublin D02 PD39 (IE)