(19)

(11)

EP 4 444 911 A2

(12)

(88) Date of publication A3: 20.07.2023 (43) Date of publication: 16.10.2024 Bulletin 2024/42 (21) Application number: 22905191.7 (22) Date of filing: 09.12.2022

(51) International Patent Classification (IPC):  C12Q 1/6869(2018.01) G06T 7/00(2017.01) G06T 7/246(2017.01) G01N 15/14(2024.01) C12Q 1/6872(2018.01) G16B 25/10(2019.01) G01N 33/49(2006.01) G16B 15/00(2019.01) (52) Cooperative Patent Classification (CPC): G16B 30/00; G16B 40/10; G06T 7/33; G06T 2207/10064; G06T 2207/30024; C12Q 1/6869   C-Sets: C12Q 1/6869, C12Q 2535/122, C12Q 2563/107; (86) International application number: PCT/US2022/052448 (87) International publication number: WO 2023/107719 (15.06.2023 Gazette 2023/24)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 10.12.2021 US 202117547602 06.06.2022 US 202263349421 P 30.06.2022 US 202217854042 11.07.2022 US 202263388183 P (71) Applicant: Element Biosciences, Inc. San Diego, California 92121 (US)

(72) Inventors: THOMPSON, Connor San Diego, California 92121 (US) LIU, Tsung-li San Diego, California 92121 (US) KRUGLYAK, Semyon San Diego, California 92121 (US) GUO, Minghao San Diego, California 92121 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)