(19)

(11)

EP 4 448 488 A2

(12)

(88) Date of publication A3: 20.07.2023 (43) Date of publication: 23.10.2024 Bulletin 2024/43 (21) Application number: 22830588.4 (22) Date of filing: 13.12.2022

(51) International Patent Classification (IPC):  C07D 209/16(2006.01) A61P 25/04(2006.01) A61P 25/16(2006.01) A61P 25/24(2006.01) A61K 31/4045(2006.01) A61P 25/06(2006.01) A61P 25/22(2006.01) A61P 25/30(2006.01) (52) Cooperative Patent Classification (CPC): C07D 209/16 (86) International application number: PCT/GB2022/053208 (87) International publication number: WO 2023/111544 (22.06.2023 Gazette 2023/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 13.12.2021 GB 202118005 13.12.2021 GB 202118008 13.12.2021 GB 202118006 13.12.2021 GB 202118011 13.12.2021 GB 202118007 14.12.2021 GB 202118095 14.12.2021 GB 202118099 15.12.2021 GB 202118156 16.12.2021 GB 202118305 16.12.2021 GB 202118295 16.12.2021 GB 202118293 16.12.2021 GB 202118309 19.08.2022 GB 202212117 19.08.2022 GB 202212113 (71) Applicant: Beckley Psytech Limited Oxford OX3 9SY (GB)

(72) Inventors: FEILDING-MELLEN, Cosmo Oxford, OX3 9SY (GB) GRAY, Jason Oxford, OX3 9SY (GB) MASON, Timothy Oxford, OX3 9SY (GB) RUDD GRETTON, Cosima Agnes Oxford, OX3 9SY (GB) WIEGAND, Frank Oxford, OX3 9SY (GB) (74) Representative: Stratagem IPM Limited  Meridian Court Comberton Road Toft, Cambridge CB23 2RY Toft, Cambridge CB23 2RY (GB)