(19)

(11)

EP 4 448 568 A1

(12)

(43) Date of publication: 23.10.2024 Bulletin 2024/43 (21) Application number: 22839650.3 (22) Date of filing: 15.12.2022

(51) International Patent Classification (IPC):  C07K 16/22(2006.01) A61P 25/02(2006.01) A61P 19/02(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/22; A61P 25/02; A61P 19/02; C07K 2317/33; C07K 2317/24; C07K 2317/92 (86) International application number: PCT/EP2022/086097 (87) International publication number: WO 2023/111157 (22.06.2023 Gazette 2023/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 16.12.2021 US 202163290264 P 04.04.2022 US 202263327076 P (71) Applicant: Intervet International B.V. 5831 AN Boxmeer (NL)	(72) Inventors: MORSEY, Mohamad Elkhorn, Nebraska 68022 (US) ZHANG, Yuanzheng Kenilworth, New Jersey 07033 (US) (74) Representative: Intervet International B.V.  Wim de Körverstraat 35 5831 AN Boxmeer 5831 AN Boxmeer (NL)