(19)

(11)

EP 4 453 194 A1

(12)

(43) Date of publication: 30.10.2024 Bulletin 2024/44 (21) Application number: 22844050.9 (22) Date of filing: 21.12.2022

(51) International Patent Classification (IPC):  C12N 9/20(2006.01) C12N 9/18(2006.01) C12P 19/38(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/18; C12P 19/38; C12Y 301/01001 (86) International application number: PCT/EP2022/087338 (87) International publication number: WO 2023/118363 (29.06.2023 Gazette 2023/26)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 22.12.2021 EP 21216948 31.05.2022 EP 22176303 (71) Applicant: BRAIN Biotech AG 64673 Zwingenberg (DE)	(72) Inventors: GODEHARD, Simon P. 64665 Alsbach-Hähnlein (DE) PELZER, Alexander 64404 Bickenbach (DE) (74) Representative: Fuchs Patentanwälte Partnerschaft mbB  Tower 185 Friedrich-Ebert-Anlage 35-37 60327 Frankfurt am Main 60327 Frankfurt am Main (DE)