(19)
(11) EP 4 457 821 A1

(12)

(43) Date of publication:
06.11.2024 Bulletin 2024/45

(21) Application number: 22856958.8

(22) Date of filing: 23.12.2022
(51) International Patent Classification (IPC): 
G16B 20/20(2019.01)
G16B 40/20(2019.01)
 G16B 30/10(2019.01)
(52) Cooperative Patent Classification (CPC):
G16B 20/20; G16B 30/10; G16B 40/20
(86) International application number:
PCT/US2022/082368
(87) International publication number:
WO 2023/129897 (06.07.2023 Gazette 2023/27)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 29.12.2021 US 202163294813 P
29.12.2021 US 202163294816 P
29.12.2021 US 202163294820 P
29.12.2021 US 202163294827 P
29.12.2021 US 202163294828 P
29.12.2021 US 202163294830 P
27.10.2022 US 202217975536
27.10.2022 US 202217975547

(71) Applicant: Illumina, Inc.
San Diego, CA 92122 (US)

(72) Inventors:
  • HAMP, Tobias
    Cambridge CB21 6DF (GB)
  • DIETRICH, Anastasia Susanna Dagmar
    Cambridge CB21 6DF (GB)
  • EDE, Jeffrey Mark
    Cambridge CB21 6DF (GB)
  • WU, Yibing
    San Diego, California 92122 (US)
  • FARH, Kai-How
    San Diego, California 92122 (US)

(74) Representative: Robinson, David Edward Ashdown 
Marks & Clerk LLP 1 New York Street
Manchester M1 4HD
Manchester M1 4HD (GB)

   


(54) MASK PATTERNS FOR PROTEIN LANGUAGE MODELS FOR PREDICTING PATHOGENICITY