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(11)

EP 4 460 698 A1

(12)

(43) Date of publication: 13.11.2024 Bulletin 2024/46 (21) Application number: 23737232.1 (22) Date of filing: 04.01.2023

(51) International Patent Classification (IPC):  G01N 33/94(2006.01) C07K 16/18(2006.01) C12N 9/04(2006.01) C12N 9/86(2006.01) C12Q 1/34(2006.01) G01N 33/68(2006.01) C07K 14/47(2006.01) C07K 16/44(2006.01) C12N 9/24(2006.01) C12Q 1/32(2006.01) G01N 33/542(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/44; C12N 9/86; G01N 33/542; C12N 9/2402; C07K 14/4728; C07K 2319/70; C07K 2319/60; C07K 2319/61; C12Y 302/01028; C07K 2317/569; G01N 2333/4727; G01N 2333/924; G01N 33/6845 (86) International application number: PCT/IB2023/020001 (87) International publication number: WO 2023/131871 (13.07.2023 Gazette 2023/28)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 05.01.2022 GB 202200051 (71) Applicant: Queensland University Of Technology Brisbane, QLD 4000 (AU)	(72) Inventors: ALEXANDROV, Kirill Brisbane Queensland 4000 (AU) GUO, Zhong Brisbane Queensland 4000 (AU) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)