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EP 4 469 034 A1

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(43) Date of publication: 04.12.2024 Bulletin 2024/49 (21) Application number: 22709370.5 (22) Date of filing: 24.01.2022

(51) International Patent Classification (IPC):  A61K 31/194(2006.01) A61K 31/734(2006.01) A61P 1/04(2006.01) A61K 47/36(2006.01) A61K 31/4172(2006.01) A61K 36/00(2006.01) A61K 9/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 1/04; A61K 31/734; A61K 31/194; A61K 31/4172; A61K 9/0065; A61K 47/36; A61K 9/006; A61K 36/33; A61K 36/05; A61K 36/185; A61K 36/60   C-Sets: A61K 36/05, A61K 2300/00; A61K 36/185, A61K 2300/00; A61K 36/60, A61K 2300/00; A61K 31/734, A61K 2300/00; A61K 31/194, A61K 2300/00; A61K 31/4172, A61K 2300/00; A61K 36/33, A61K 2300/00; (86) International application number: PCT/IB2022/050584 (87) International publication number: WO 2023/139414 (27.07.2023 Gazette 2023/30)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicants: Metis Healthcare S.r.L. 20121 Milano (IT) ADVENTIA PHARMA, S.L. 35002 Las Palmas de Gran Canaria (ES)	(72) Inventors: NENZIONI, Davide 20121 Milano (IT) BARON, Giovanna 20121 Milano (IT) (74) Representative: Croce, Valeria et al Jacobacci & Partners S.p.A. Via Senato, 8 20121 Milano 20121 Milano (IT)